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Document Details
Document Type
:
Thesis
Document Title
:
Effect of cinnamon on plasma glucose concentration and the regulation of 6-phosphofructo-1-kinase activity from the liver and small intestine of streptozotocin induced diabetic rats
تأثير القرفة على تركيز الجلوكوز في البلازما و تنظيم نشاطية 6- فوسفو فركتو-1- كينيز من كبد و أمعاء الجرذان المصابة بداء السكري المستحث بالاستربتوزوتوسين
Subject
:
Biochemistry
Document Language
:
Arabic
Abstract
:
This research attempts to elucidate the effect of cinnamon, a kind of spices commonly used in Eastern and Middle-eastern countries in their food, on plasma glucose concentration and the regulation of 6- phosphofructo-1-kinase in streptozotocin induced-diabetic rats. The animals were 50 male Wistar rats (180-200 g) divided into five groups: normal controls, untreated diabetics (rats were made diabetic by single I.P. injection of streptozotocin), diabetics rats treated with 0.5g and 1.0g of cinnamon, and the last group of diabetic rats were treated with insulin. This study is concerned with the regulation glucose metabolism in streptozotocin- induced diabetic rats by an estimate of enzyme activity of liver and small intestine. Also, to demonstrate the effect of cinnamon on plasma glucose, cholesterol, triacylglycerol and insulin concentrations. In addition, the present study compares the regulation of PFK-1 of the diabetic rats with another group of diabetic rats treated with cinnamon. The results show a significant decrease (p < 0.0001) in glucose, cholesterol and triacylglycerol concentrations were a significant increase (p < 0.0001) in insulin concentration and the enzyme activity in cinnamon treated groups. In conclusion, cinnamon have a scientific evidence to improve diabetes safely
Supervisor
:
Prof. Samir Mohamed Khoja
Thesis Type
:
Master Thesis
Publishing Year
:
1427 AH
2006 AD
Added Date
:
Tuesday, June 10, 2008
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
سونهام سامي يغمور
Yaghmour, Ssounaam Sami
Researcher
Master
Files
File Name
Type
Description
24252.pdf
pdf
المستخلص
24253.pdf
pdf
Abstract
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