Main Page
About Science
Faculty Deanship
Letter of Dean
Overview of Deanship
Vice Deans
Vice Dean
Letter of Vice-dean
Overview of Vice-deanship
Vice Dean for Graduate Studies
Letter of Vice Dean for Graduate Studies
Overview of Vice Dean of Postgraduate Studies
Research and Innovation Unit
Vice Dean for Girls Campus
Faculty Management
Letter of Managing Director-Boys Campus
Letter of Managing Director-Girls Campus
Overview of Management
Educational Affairs
Males Campus
Staff
Females Campus
Contact Us
Research
عربي
English
About
Admission
Academic
Research and Innovations
University Life
E-Services
Search
Faculty of Sciences
Document Details
Document Type
:
Article In Journal
Document Title
:
Synthesis and biological evaluation of some new triazolo- and triazinophthalazines
Synthesis and biological evaluation of some new triazolo- and triazinophthalazines
Document Language
:
Arabic
Abstract
:
Abstract: Condensation of hydralazine 1 with ethyl oxalate afforded triazinodione 3 or s-triazolo derivative 4, while with alpha-bromo ketones, 1,2-cyclohexanedione and pyridine keto acid it gave the as-triazino derivatives a-a respectively. Reaction of 1 with bromo esters yield the corresponding 3-bromo-alkyl s-triazolophthalazines 9. Condensation of 9a with hydrazine hydrate followed by acetylacetone afforded the pyrazole derivative ii. Cyclization of 1 with acid chlorides or ketones gave the appropriate 3-substitutes s-triazolophthalazines. With chloromalonic acid ester, 1 yielded the triazino-triazolo derivative 18, while with pyridine acetal it gave the his s-triazolophthalazine 19.
Journal Name
:
Source: AFINIDAD
Volume
:
55
Issue Number
:
475
Publishing Year
:
1998 AH
Added Date
:
Saturday, June 14, 2008
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
سالم أحمد باسيف
Researcher
Back To Researches Page