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Document Details
Document Type
:
Article In Journal
Document Title
:
S- to N-Acyl transfer in S-acylcysteine isopeptides via 9-, 10-, 12-, and 13-membered cyclic transition states
S- to N-Acyl transfer in S-acylcysteine isopeptides via 9-, 10-, 12-, and 13-membered cyclic transition states
Document Language
:
English
Abstract
:
S-Acyl cysteine peptides containing alpha-, beta- or gamma-amino acid residues undergo long-range S- to N-acyl transfer to give analogs of native tripeptides and tetrapeptides containing additional carbon atoms in the chain. The ease of intramolecular S -> N-acyl transfer relative to intermolecular transacylation is favored increasingly for 9?12?13?similar to?10-membered cyclic transition states; the observed order is explained on conformational and intermolecular interaction considerations
ISSN
:
1075-2617
Journal Name
:
JOURNAL OF PEPTIDE SCIENCE
Volume
:
18
Issue Number
:
11
Publishing Year
:
1433 AH
2012 AD
Article Type
:
Article
Added Date
:
Wednesday, July 12, 2017
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
O Bol'shakov
Bol'shakov, O
Researcher
J Kovacs
Kovacs, J
Researcher
M Chahar
Chahar, M
Researcher
H Khanh
Khanh, H
Researcher
l Khelashvili
Khelashvili, l
Researcher
A Katritzky
Katritzky, A
Researcher
Files
File Name
Type
Description
42086.pdf
pdf
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