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Document Details
Document Type
:
Article In Journal
Document Title
:
Synthesis of Novel Schiff Bases by Microwave Irradiation and Their in vitro Antibacterial Activity
Synthesis of Novel Schiff Bases by Microwave Irradiation and Their in vitro Antibacterial Activity
Document Language
:
English
Abstract
:
A series of thiophene-3-carbonitrile contaning schiff bases were synthesized, characterized by the reaction of 2-amino-4,5,6,7-tetrahydro-benzo[b] thiophene-3-carbonitrile and corresponding active aldehyde under microwave irradiation and screened for their antibacterial activities. The structure of synthesized compounds were established by spectroscopic (FT-IR, H-1 NMR, C-13 NMR, Mass) and elemental analyses. The antibacterial activity of these compounds were first tested in vitro by the disk diffusion assay against two Gram-positive and two Gram-negative bacteria and then the minimum inhibitory concentration was determined with the reference of standard drug chloramphenicol. The results showed that compound 6 is better at inhibiting the growth as compared to chloramphenicol against both types of the bacteria (gram-positive and gram-negative).
ISSN
:
0970-7077
Journal Name
:
ASIAN JOURNAL OF CHEMISTRY
Volume
:
25
Issue Number
:
15
Publishing Year
:
1434 AH
2013 AD
Article Type
:
Article
Added Date
:
Wednesday, July 19, 2017
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
S Khan
Khan, S
Researcher
A Asiri
Asiri, A
Researcher
A Khan
Khan, A
Researcher
K Khan
Khan, K
Researcher
A Zayed
Zayed, A
Researcher
Files
File Name
Type
Description
42110.pdf
pdf
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